- What is Y-DNA and how does it apply to genealogy?
- How do I join the project ?
- Where can I find more information on DNA studies?
- Why can't DNA from women be used for this project?
- How long does it take to get results from a test?
- What is Genetic Distance?
Other answers may be found at FamilyTreeDNA
DNA is the basic building block for all life on Earth. DNA is organized in long, twisted strands of molecules. These strands are further combined into "packages" called chromosomes. Each human has 23 pairs of chromosomes. Half of each chromosome pair is derived from the individual's mother, the other half from the father. The 23rd chromosome pair is the one that determines the person's gender. In males, this pair consists of one "X" chromosome and one "Y" chromosome. Females have two "X" chromosomes. The Y chromosome is passed virtually unchanged from a father to his sons. Consequently, two males living today who share a common male ancestor could be expected to have identical Y chromosomes. The Y-DNA used for this project is based on a series of "junk" DNA sequences present on the Y chromosome. These sequences do not contain critical information needed by the human body and none of the information can be used to identify a specific individual. Testing of this portion of the Y chromosome provides information about the direct male line–father to father to father and so forth back through time. The locations tested on the Y chromosome are called Markers. Occasionally a mutation occurs at one of the Markers in the Y chromosome. A mutation is simply a small change in the way the molecules are assembled. These occasional mutations, which are estimated to occur about once every 500 generations per Marker, form the statistical basis for y-DNA genealogical studies. If you have further questions, email the project administrator at admin@dna.rdgriffith.com.
This project is intended for individuals with a direct paternal lineage to a DuBose/DuBois(e) ancestor. To join the project, please complete the enrollment form at the following link. Order Form If you have problems accessing the on-line form, contact the administrator at admin@dna.rdgriffith.com, or call 309-694-3569.
The set of markers used for this type of study are taken from the Y-Chromosome, which is only passed from a father to his sons. Daughters receive two X-Chromosomes, so the markers are not present in the DNA sample from a female.
The average time for lab procedures is about 6 weeks. Actual dates may vary due to the number of kits in your batch, as well as the need to re-run the sample.
If you have ordered an extended Y-DNA test you’ll most likely receive the first 12 markers back followed in a few days by the next set of 13 markers. Quality Control is very strict about 2 sets of eyes confirming every score. This takes a little longer, but it also dramatically reduces the chance that an incorrect score is reported!
If more than a week went by from the targeted date without your results being posted, it means that most probably we did not get a result on the first pass during the sequencing process. From our lab's experience this happens in about 10 - 15% of the times. This can be caused by a number of factors, such as a poor scrape, or a marker may produce a "dual peak" where a single peak is expected.
In all of these cases we will re-run the entire sequence from the same DNA that was extracted from vial A. This will produce a complete new set of scores for your sample. The two sets are compared, and the geneticist makes a determination. If once again the results are incomplete we then extract the DNA from vial B and start the above process again.
The lack of results after this series of attempts (2 from vial A and 2 from vial B) will prompt us to send you a new kit (free of charge) for a new scraping, as the initial samples didn't give the lab enough quality DNA to work from. Although this adds to the delivery time, it ensures that we report accurate results, so please bear with us as in the final analysis accuracy is far more important than speed.
Genetic distance is a term used to describe the degree of mismatch between two Y-DNA test results. In general, the greater the genetic distance between two DNA samples, the further you must go back in time to find a common ancestor. While genetic distance can be a useful way to evaluate the likelihood of relatedness, it should not be considered "proof" of relatedness. The science of genetics is still evolving and there are several different methods currently being used to calculate genetic distance. The calculation algorithm used for this project produces similar results as the one used by the FTDNA Genetic Distance Report.
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